Guidelines for Diabetes in Pregnancy / Gestational Diabetes Mellitus
Including Early GDM, DIPSI, EGGI, and Metformin Recommendations: A Comparative Clinical Summary
Amit Kumar 1, Chandan Kumar 2*
- Associate Prof Dr Amit Kumar, Department of Community Medicine, Dr BS Kushwah Institute of Medical Sciences, Kanpur, India;
Corresponding author*: Dr Chandan Kumar, MD, Department of Community Medicine, Dr BS Kushwah Institute of Medical Sciences,
Kanpur, India; email: [email protected]
Submitted: 24 June 2026; Accepted: 10 July 2026; Published: 22 July 2026
There is no single global consensus on how to screen for and diagnose gestational diabetes mellitus (GDM).
The major divide is between the one-step approach (75g OGTT, IADPSG-derived thresholds, adopted by WHO, ADA, and most of the world) and the two-step approach (50g glucose challenge test followed by 100g OGTT, used in the United States by
ACOG). Separate, less standardized guidance also exists for “Early GDM” — screening and diagnosis before 24 weeks, generally before 15–20 weeks — including India-specific frameworks such as DIPSI and the emerging EGGI concept.
