{"id":1704,"date":"2025-09-11T08:17:03","date_gmt":"2025-09-11T08:17:03","guid":{"rendered":"https:\/\/diabetesasia.org\/journal\/?p=1704"},"modified":"2026-04-25T06:48:10","modified_gmt":"2026-04-25T06:48:10","slug":"do-microplastics-have-any-significant-effect-on-red-blood-cells-an-in-depth-study-bysystematic-review-and-meta-analysis","status":"publish","type":"post","link":"https:\/\/www.diabetesasia.org\/journal\/do-microplastics-have-any-significant-effect-on-red-blood-cells-an-in-depth-study-bysystematic-review-and-meta-analysis\/","title":{"rendered":"Do Microplastics have any significant effect on Red Blood Cells? An In-depth study bySystematic Review and Meta-Analysis"},"content":{"rendered":"\n<p><strong>Do Microplastics have any significant effect on Red Blood Cells? An In-depth Study by Systematic Review and Meta-Analysis<\/strong><\/p>\n\n\n\n<p><strong>Abstract<\/strong><\/p>\n\n\n\n<p><strong>Background:<\/strong> Despite growing interest, a critical knowledge gap remains regarding the toxicodynamic interactions between MPs and human erythrocytes. This study was done to consolidate emerging evidence on microplastics\u2019 effects on red blood cells and interpret their implications for public health. Methodology: In this study, studies were identified from multiple databases such as PubMed, Cochrane Reviews, and Google Scholar, and all types of data in any form of article were retrieved using 2 keywords: \u201cMicroplastics\u201d and \u201cRBC\u201d from the last 20 years in the Literature.<\/p>\n\n\n\n<p><strong>Results:<\/strong>\u00a0 This systematic review of\u00a0\u00a0 63\u00a0\u00a0 articles provides consolidated evidence that MNPs interact directly with erythrocytes (RBCs), leading to oxidative damage, impaired deformability, and disruptions in oxygen transport. These effects are not isolated but form part of a broader cascade involving endothelial dysfunction, immune activation, and vascular complications. <strong>Most included studies report a statistically significant increase in hemolysis associated with the exposure under investigation, with effect sizes ranging from moderate (6%) to large (10%). <\/strong>\u00a0<\/p>\n\n\n\n<p><strong>Conclusion:<\/strong> Given the pervasive presence of microplastics in the environment, including recent confirmation of their presence in human blood, these findings raise significant concerns about their potential hematological and systemic health effects. Regulatory bodies and public health institutions must prioritize further investigation, public.<\/p>\n\n\n\n<p>Keywords: Microplastics, Red Blood Cells, Human Blood, Systematic<br>Review, Meta-Analysis<\/p>\n\n\n\n<div data-wp-interactive=\"core\/file\" class=\"wp-block-file\"><object data-wp-bind--hidden=\"!state.hasPdfPreview\" hidden class=\"wp-block-file__embed\" data=\"https:\/\/diabetesasia.org\/journal\/wp-content\/uploads\/2025\/09\/DAJ-VOl2-Issue-2-107-137.pdf\" type=\"application\/pdf\" style=\"width:100%;height:600px\" aria-label=\"Embed of DAJ VOl2 Issue 2 107-137..\"><\/object><a id=\"wp-block-file--media-595e9ff2-43fc-4538-9e2e-bc760b9f38ec\" href=\"https:\/\/diabetesasia.org\/journal\/wp-content\/uploads\/2025\/09\/DAJ-VOl2-Issue-2-107-137.pdf\">DAJ VOl2 Issue 2 107-137.<\/a><a href=\"https:\/\/diabetesasia.org\/journal\/wp-content\/uploads\/2025\/09\/DAJ-VOl2-Issue-2-107-137.pdf\" class=\"wp-block-file__button wp-element-button\" download aria-describedby=\"wp-block-file--media-595e9ff2-43fc-4538-9e2e-bc760b9f38ec\">Download<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Do Microplastics have any significant effect on Red Blood Cells? An In-depth Study by Systematic Review and Meta-Analysis Abstract Background: Despite growing interest, a critical knowledge gap remains regarding the toxicodynamic interactions between MPs and human erythrocytes. This study was done to consolidate emerging evidence on microplastics\u2019 effects on red blood cells and interpret their implications for public health. Methodology: In this study, studies were identified from multiple databases such as PubMed, Cochrane Reviews, and Google Scholar, and all types of data in any form of article were retrieved using 2 keywords: \u201cMicroplastics\u201d and \u201cRBC\u201d from the last 20 years in the Literature. Results:\u00a0 This systematic review of\u00a0\u00a0 63\u00a0\u00a0 articles provides consolidated evidence that MNPs interact directly with erythrocytes (RBCs), leading to oxidative damage, impaired deformability, and disruptions in oxygen transport. These effects are not isolated but form part of a broader cascade involving endothelial dysfunction, immune activation, and vascular complications. Most included studies report a statistically significant increase in hemolysis associated with the exposure under investigation, with effect sizes ranging from moderate (6%) to large (10%). \u00a0 Conclusion: Given the pervasive presence of microplastics in the environment, including recent confirmation of their presence in human blood, these findings raise significant concerns about their potential hematological and systemic health effects. Regulatory bodies and public health institutions must prioritize further investigation, public. Keywords: Microplastics, Red Blood Cells, Human Blood, SystematicReview, Meta-Analysis<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1,86],"tags":[116,114,36,115],"class_list":["post-1704","post","type-post","status-publish","format-standard","hentry","category-blog","category-vol-2-issue-2","tag-analysis","tag-meta-analysis","tag-microplastics","tag-rbc"],"_links":{"self":[{"href":"https:\/\/www.diabetesasia.org\/journal\/wp-json\/wp\/v2\/posts\/1704","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.diabetesasia.org\/journal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.diabetesasia.org\/journal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.diabetesasia.org\/journal\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.diabetesasia.org\/journal\/wp-json\/wp\/v2\/comments?post=1704"}],"version-history":[{"count":0,"href":"https:\/\/www.diabetesasia.org\/journal\/wp-json\/wp\/v2\/posts\/1704\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.diabetesasia.org\/journal\/wp-json\/wp\/v2\/media?parent=1704"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.diabetesasia.org\/journal\/wp-json\/wp\/v2\/categories?post=1704"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.diabetesasia.org\/journal\/wp-json\/wp\/v2\/tags?post=1704"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}