{"id":6263,"date":"2022-07-16T15:07:53","date_gmt":"2022-07-16T09:37:53","guid":{"rendered":"https:\/\/www.diabetesasia.org\/magazine\/?p=6263"},"modified":"2024-11-23T11:01:08","modified_gmt":"2024-11-23T05:31:08","slug":"monkeypox-spread","status":"publish","type":"post","link":"https:\/\/www.diabetesasia.org\/magazine\/monkeypox-spread\/","title":{"rendered":"Monkeypox Spread"},"content":{"rendered":"<h2>Monkeypox Spread:<\/h2>\n<div class=\"flex max-w-full flex-col flex-grow\">\n<div class=\"min-h-8 text-message flex w-full flex-col items-end gap-2 whitespace-normal break-words [.text-message+&amp;]:mt-5\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"b682b28c-3154-4b85-a704-d871166e94ed\" data-message-model-slug=\"gpt-4o-mini\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[3px]\">\n<div class=\"markdown prose w-full break-words dark:prose-invert light\">\n<p>The 2022 <span style=\"color: #0000ff;\"><strong><a style=\"color: #0000ff;\" href=\"https:\/\/en.wikipedia.org\/wiki\/Monkeypox\">monkeypox<\/a> <\/strong><\/span>outbreak began in May and was a significant global health event. The first confirmed case was traced to an individual with travel links to Nigeria, where the disease is endemic, and was detected on May 6, 2022, in the <span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/en.wikipedia.org\/wiki\/United_Kingdom\">United Kingdom<\/a><\/span>. This initial case sparked concerns as it began an outbreak spanning several countries and continents.<\/p>\n<p>From May 18 onward, monkeypox cases were reported in multiple regions, including Europe, North and South America, Asia, Africa, and Australia. Previously confined to certain areas of Central and West Africa, the disease spread more widely during this outbreak, with cases detected in areas where the virus was not commonly seen.<\/p>\n<p>By July 15, 12,590 confirmed cases had been recorded, with 12 deaths recorded. The World Health Organization (WHO) acknowledged the growing concern but, as of June 27, did not declare it a Public Health Emergency of International Concern (PHEIC). Instead, the WHO categorized the situation as an &#8220;evolving health threat,&#8221; suggesting the outbreak was being closely monitored but did not yet warrant the highest level of international health alert.<\/p>\n<p>The spread of the virus sparked increased attention on public health measures, including tracking and managing close contacts. The global community began working together to contain the outbreak, with measures including vaccines and antiviral treatments being discussed and deployed.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>The outbreak marked the first time the disease has spread widely outside Central and West Africa. Cases have mainly but not exclusively been identified amongst\u00a0men who have sex with men (MSM). Still, health authorities emphasized that anyone can catch the disease, particularly if they have close contact with a symptomatic person. <sup id=\"cite_ref-WHO13_5-1\" class=\"reference\"><\/sup>Initial <strong><span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/en.wikipedia.org\/wiki\/World_Health_Organization\">WHO<\/a> <\/span><\/strong>assessments expressed the expectation that the outbreak would be contained and have a low impact on the general population in affected countries.<sup id=\"cite_ref-WHO13_5-2\" class=\"reference\"><\/sup><sup id=\"cite_ref-18\" class=\"reference\"><\/sup> A more recent statement acknowledged that undetected transmission had occurred for some time and\u00a0called for urgent action to reduce transmission.<sup id=\"cite_ref-20\" class=\"reference\"><\/sup><sup id=\"cite_ref-CNBC-undetected-spread_21-0\" class=\"reference\"><\/sup><\/p>\n<p>Monkeypox is a viral infection that manifests a week or two after exposure to fever and other <a class=\"mw-redirect\" title=\"Non-specific symptoms\" href=\"https:\/\/en.wikipedia.org\/wiki\/Non-specific_symptoms\">non-specific symptoms<\/a>. It then produces a\u00a0<a title=\"Rash\" href=\"https:\/\/en.wikipedia.org\/wiki\/Rash\">rash<\/a>\u00a0with blisters that can last for a couple of weeks before usually clearing up.<sup id=\"cite_ref-WHO12_7-1\" class=\"reference\"><\/sup> In infections before the current outbreak, 1\u20133% of people with known diseases have died (without treatment). Cases in children are more likely to be severe.<sup id=\"cite_ref-WHO13_5-3\" class=\"reference\"><\/sup><\/p>\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"wp-image-6268 aligncenter\" src=\"https:\/\/i0.wp.com\/www.diabetesasia.org\/magazine\/wp-content\/uploads\/2022\/07\/in-monkeypox_lesions.webp?resize=410%2C231&#038;ssl=1\" alt=\"Monkeypox\" width=\"410\" height=\"231\" srcset=\"https:\/\/i0.wp.com\/www.diabetesasia.org\/magazine\/wp-content\/uploads\/2022\/07\/in-monkeypox_lesions.webp?resize=300%2C169&amp;ssl=1 300w, https:\/\/i0.wp.com\/www.diabetesasia.org\/magazine\/wp-content\/uploads\/2022\/07\/in-monkeypox_lesions.webp?w=480&amp;ssl=1 480w\" sizes=\"auto, (max-width: 410px) 100vw, 410px\" \/><\/p>\n<p><a title=\"Monkeypox\" href=\"https:\/\/en.wikipedia.org\/wiki\/Monkeypox\">Monkeypox<\/a>\u00a0is an infectious\u00a0<a title=\"Viral disease\" href=\"https:\/\/en.wikipedia.org\/wiki\/Viral_disease\">viral disease<\/a> that can occur in humans and other animals. <sup id=\"cite_ref-Monkeypox_WHO4June2022_22-0\" class=\"reference\"><\/sup>Symptoms include\u00a0<a title=\"Fever\" href=\"https:\/\/en.wikipedia.org\/wiki\/Fever\">fever<\/a>,\u00a0<a title=\"Lymphadenopathy\" href=\"https:\/\/en.wikipedia.org\/wiki\/Lymphadenopathy\">swollen lymph nodes<\/a>, and a rash that forms\u00a0<a class=\"mw-redirect\" title=\"Blisters\" href=\"https:\/\/en.wikipedia.org\/wiki\/Blisters\">blisters<\/a> and then crusts over.\u00a0<sup id=\"cite_ref-Monkeypox_WHO4June2022_22-1\" class=\"reference\"><\/sup>The time from\u00a0<a title=\"Incubation period\" href=\"https:\/\/en.wikipedia.org\/wiki\/Incubation_period\">exposure to onset<\/a>\u00a0of symptoms ranges from 5 to 21 days.<sup id=\"cite_ref-Monkeypox_WHOfact2022_23-0\" class=\"reference\"><\/sup><sup id=\"cite_ref-Monkeypox_CDC2017Sym_24-0\" class=\"reference\"><\/sup> The duration of symptoms is typically 2 to 4 weeks.\u00a0<sup id=\"cite_ref-Monkeypox_CDC2017Sym_24-1\" class=\"reference\"><\/sup>There may be mild symptoms, but they may occur without known symptoms.<sup id=\"cite_ref-Monkeypox_WHOfact2022_23-1\" class=\"reference\"><\/sup><sup id=\"cite_ref-Monkeypox_Sut2020_25-0\" class=\"reference\"><\/sup>\u00a0The classic presentation of fever and\u00a0<a title=\"Myalgia\" href=\"https:\/\/en.wikipedia.org\/wiki\/Myalgia\">muscle pains<\/a>, followed by\u00a0<a class=\"mw-redirect\" title=\"Swollen glands\" href=\"https:\/\/en.wikipedia.org\/wiki\/Swollen_glands\">swollen glands<\/a>\u00a0with lesions at the same stage, is not expected in all outbreaks.<sup id=\"cite_ref-Monkeypox_WHO4June2022_22-2\" class=\"reference\"><\/sup><sup id=\"cite_ref-Monkeypox_Harris2022_26-0\" class=\"reference\"><\/sup> Cases may be severe, especially in children, pregnant women, or people with suppressed immune systems.<sup id=\"cite_ref-Monkeypox_WHO13_27-0\" class=\"reference\"><\/sup><\/p>\n<p>There is no known cure. <sup id=\"cite_ref-Monkeypox_CDC2019Tx_32-0\" class=\"reference\"><\/sup>A study in 1988 found that the\u00a0<a title=\"Smallpox vaccine\" href=\"https:\/\/en.wikipedia.org\/wiki\/Smallpox_vaccine\">smallpox vaccine<\/a> was around 85% protective in preventing infection in close contact and lessening the severity of the disease.<sup id=\"cite_ref-33\" class=\"reference\"><\/sup>\u00a0A newer\u00a0<a class=\"mw-redirect\" title=\"Jynneos\" href=\"https:\/\/en.wikipedia.org\/wiki\/Jynneos\">smallpox and monkeypox vaccine<\/a>\u00a0based on\u00a0<a title=\"Modified vaccinia Ankara\" href=\"https:\/\/en.wikipedia.org\/wiki\/Modified_vaccinia_Ankara\">modified vaccinia Ankara<\/a> has been approved but has limited availability.<sup id=\"cite_ref-Monkeypox_WHOfact2022_23-2\" class=\"reference\"><\/sup>\u00a0Other measures include regular hand washing and avoiding sick people and other animals.<sup id=\"cite_ref-Monkeypox_CDCprev_34-0\" class=\"reference\"><\/sup>\u00a0<a class=\"mw-redirect\" title=\"Antiviral drugs\" href=\"https:\/\/en.wikipedia.org\/wiki\/Antiviral_drugs\">Antiviral drugs<\/a>, including cidofovir and tecovirimat, vaccinia immune globulin, and the smallpox vaccine, may be used during outbreaks.<sup id=\"cite_ref-Monkeypox_CDC26may2022_35-0\" class=\"reference\"><\/sup><sup id=\"cite_ref-Monkeypox_Gov.UK2022_36-0\" class=\"reference\"><\/sup> The illness is usually mild, and most infected will recover within a few weeks without treatment.<sup id=\"cite_ref-Monkeypox_Gov.UK2022_36-1\" class=\"reference\"><\/sup>\u00a0Estimates of the risk of death vary from 1% to 10%, although very few deaths as a consequence of monkeypox have been recorded since 2017.<sup id=\"cite_ref-37\" class=\"reference\"><\/sup><\/p>\n<p>Monkeypox is endemic to West and Central Africa. <sup id=\"cite_ref-Bunge2022_48-0\" class=\"reference\"><\/sup><sup id=\"cite_ref-49\" class=\"reference\"><\/sup>Before the 2022 outbreak, the United Kingdom had recorded only seven previous cases of monkeypox,<sup id=\"cite_ref-bbc-scotland_50-0\" class=\"reference\"><\/sup> all of which were imported issues from Africa or healthcare workers involved in their treatment. The first three cases were in 2018,<sup id=\"cite_ref-bbc-scotland_50-1\" class=\"reference\"><\/sup> followed by another point in 2019,<sup id=\"cite_ref-PHE4Dec2019_51-0\" class=\"reference\"><\/sup> and three more in 2021.<sup id=\"cite_ref-:0_52-0\" class=\"reference\"><\/sup> The only major monkeypox outbreak recorded in a\u00a0<a title=\"Western world\" href=\"https:\/\/en.wikipedia.org\/wiki\/Western_world\">Western country<\/a> before 2022 was the\u00a02003 Midwest monkeypox outbreak\u00a0in the United States. That one did not feature community transmission.<sup id=\"cite_ref-53\" class=\"reference\"><\/sup><sup id=\"cite_ref-54\" class=\"reference\"><\/sup><\/p>\n<p>According to the World Health Organization, this outbreak occurred in West Africa. There is a reported case fatality rate of 1%.<sup id=\"cite_ref-55\" class=\"reference\"><\/sup> Portuguese researchers first published the genomic sequence of the virus associated with this outbreak on May 19.<sup id=\"cite_ref-:8_56-0\" class=\"reference\"><\/sup>\u00a0They confirmed that the <a href=\"https:\/\/www.diabetesasia.org\/magazine\/what-is-monkeypox-and-the-way-do-you-seize-it\/\">monkeypox virus<\/a> was of the West African cladeCladeated to other previous international epidemics in 2018\u201319.<sup id=\"cite_ref-:9_57-0\" class=\"reference\"><\/sup><\/p>\n<h4 class=\"text-gray-900 font-bold leading-rem24px text-rem20px bp600:text-rem25px bp600:leading-rem30px mt-rem32px mb-rem16px break-words \" data-identity=\"headline\">Types of pox<\/h4>\n<p class=\"text-gray-800 my-rem16px text-rem19px leading-rem34px \" data-identity=\"paragraph-element\">There are two known subtypes of pox:<\/p>\n<ul class=\"my-rem16px mx-0 pl-[1.25rem] list-disc marker:text-brandBlue-500 marker:pl-rem24px \" data-identity=\"unordered-list\">\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Clade I is endemic to Central Africa and tends to cause more serious illness than Clade II. Recent outbreaks of CladeCladeve have been less deadly.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Clade II is endemic to East Africa. There has been a global outbreak of clade II pox since 2022. It is less likely to be fatal than cladeCladehat. What are the symptoms of the pox?<\/li>\n<li>\n<p class=\"text-gray-800 my-rem16px text-rem19px leading-rem34px \" data-identity=\"paragraph-element\">Symptoms of pox include:<\/p>\n<ul class=\"my-rem16px mx-0 pl-[1.25rem] list-disc marker:text-brandBlue-500 marker:pl-rem24px \" data-identity=\"unordered-list\">\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\"><a class=\"text-brandBlue-500 underline underline-offset-[5px] decoration-1 break-words hover:text-blue-800 transition\" href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/17413-rashes-red-skin\" target=\"_blank\" rel=\"noopener\" data-identity=\"link\">Rash<\/a>, skin ulcers, or blisters.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\"><a class=\"text-brandBlue-500 underline underline-offset-[5px] decoration-1 break-words hover:text-blue-800 transition\" href=\"https:\/\/my.clevelandclinic.org\/health\/symptoms\/10880-fever\" target=\"_blank\" rel=\"noopener\" data-identity=\"link\">Fever<\/a>.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Swollen lymph nodes.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\"><a class=\"text-brandBlue-500 underline underline-offset-[5px] decoration-1 break-words hover:text-blue-800 transition\" href=\"https:\/\/my.clevelandclinic.org\/health\/symptoms\/21476-chills\" target=\"_blank\" rel=\"noopener\" data-identity=\"link\">Chills<\/a>.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Headache.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Muscle aches.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Fatigue.<\/li>\n<\/ul>\n<p class=\"text-gray-800 my-rem16px text-rem19px leading-rem34px \" data-identity=\"paragraph-element\">Not everyone with pox develops all the symptoms. Different ways you might experience symptoms include:<\/p>\n<ul class=\"my-rem16px mx-0 pl-[1.25rem] list-disc marker:text-brandBlue-500 marker:pl-rem24px \" data-identity=\"unordered-list\">\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Only a rash (no other symptoms), or other symptoms developing later.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Flu-like symptoms, then a rash. Some people don&#8217;t get a rash at all.<\/li>\n<\/ul>\n<h4 class=\"text-gray-900 font-bold leading-rem24px text-rem20px bp600:text-rem25px bp600:leading-rem30px mt-rem32px mb-rem16px break-words \" data-identity=\"headline\">What does the pox rash look like?<\/h4>\n<p class=\"text-gray-800 my-rem16px text-rem19px leading-rem34px \" data-identity=\"paragraph-element\">The rash caused by pox can appear as sores on your mouth, face, hands, feet, penis, vagina, or anus (butthole). Some people have a widespread rash, but others only have a few bumps or blisters.<\/p>\n<p class=\"text-gray-800 my-rem16px text-rem19px leading-rem34px \" data-identity=\"paragraph-element\">Mpox rash can go through several stages over two to four weeks:<\/p>\n<ol class=\"my-rem16px mx-0 pl-rem24px list-decimal marker:pl-rem24px marker:text-brandBlue-500 marker:font-semibold \" data-identity=\"ordered-list\">\n<li class=\"text-gray-800 mb-rem12px text-rem19px leading-rem34px pl-rem12px\">It may start as flat, red bumps. These can be painful.<\/li>\n<li class=\"text-gray-800 mb-rem12px text-rem19px leading-rem34px pl-rem12px\">The bumps become raised.<\/li>\n<li class=\"text-gray-800 mb-rem12px text-rem19px leading-rem34px pl-rem12px\">The bumps turn into\u00a0<a class=\"text-brandBlue-500 underline underline-offset-[5px] decoration-1 break-words hover:text-blue-800 transition\" href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/16787-blisters\" target=\"_blank\" rel=\"noopener\" data-identity=\"link\">blisters<\/a>.<\/li>\n<li class=\"text-gray-800 mb-rem12px text-rem19px leading-rem34px pl-rem12px\">The blisters fill with pus.<\/li>\n<li class=\"text-gray-800 mb-rem12px text-rem19px leading-rem34px pl-rem12px\">The blisters crust over and fall off.<\/li>\n<\/ol>\n<h3 class=\"text-gray-900 font-bold leading-rem30px text-rem25px bp600:text-rem32px bp600:leading-rem38px mt-rem32px mb-rem16px break-words \" data-identity=\"headline\">What causes mpox?<\/h3>\n<p class=\"text-gray-800 my-rem16px text-rem19px leading-rem34px \" data-identity=\"paragraph-element\">An infection with the monkeypox virus (<em>Orthopoxvirus monkeypox<\/em>) causes pox. Viruses are small pieces of genetic information in a protective coating. The virus that causes pox is a member of the genus <em><a class=\"text-brandBlue-500 underline underline-offset-[5px] decoration-1 break-words hover:text-blue-800 transition\" href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/orthopoxvirus\" target=\"_blank\" rel=\"noopener\" data-identity=\"link\">Orthopoxvirus<\/a>.<\/em><\/p>\n<h4 class=\"text-gray-900 font-bold leading-rem24px text-rem20px bp600:text-rem25px bp600:leading-rem30px mt-rem32px mb-rem16px break-words \" data-identity=\"headline\">How do you get mpox?<\/h4>\n<p class=\"text-gray-800 my-rem16px text-rem19px leading-rem34px \" data-identity=\"paragraph-element\">Mpox can spread through:<\/p>\n<ul class=\"my-rem16px mx-0 pl-[1.25rem] list-disc marker:text-brandBlue-500 marker:pl-rem24px \" data-identity=\"unordered-list\">\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Direct contact with pox sores or scabs (from an animal or person).<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Contact with\u00a0<a class=\"text-brandBlue-500 underline underline-offset-[5px] decoration-1 break-words hover:text-blue-800 transition\" href=\"https:\/\/my.clevelandclinic.org\/health\/body\/saliva\" target=\"_blank\" rel=\"noopener\" data-identity=\"link\">saliva<\/a>\u00a0(spit), respiratory secretions from your nose or mouth (<a class=\"text-brandBlue-500 underline underline-offset-[5px] decoration-1 break-words hover:text-blue-800 transition\" href=\"https:\/\/my.clevelandclinic.org\/health\/body\/mucus\" target=\"_blank\" rel=\"noopener\" data-identity=\"link\">mucus<\/a>), blood, or other bodily fluids (from an animal or person).<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Contact with materials like clothing, bedding, and towels an infected person uses is dismal.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Vertical transmission \u2014 from a pregnant person to their fetus during pregnancy or at birth.<\/li>\n<\/ul>\n<p class=\"text-gray-800 my-rem16px text-rem19px leading-rem34px \" data-identity=\"paragraph-element\">Specific situations that can spread pox include:<\/p>\n<ul class=\"my-rem16px mx-0 pl-[1.25rem] list-disc marker:text-brandBlue-500 marker:pl-rem24px \" data-identity=\"unordered-list\">\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Close, intimate contact, like cuddling, kissing, or sex. Though less likely, it&#8217;s possible that you could spread pox by talking, sneezing, or coughing very close to others.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Skin-to-skin contact sharing personal items, like towels, bedding, or sex toys.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Bites or scratches from an infected animal.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">They are eating the meat of an infected animal.<\/li>\n<\/ul>\n<h4 class=\"text-gray-900 font-bold leading-rem24px text-rem20px bp600:text-rem25px bp600:leading-rem30px mt-rem32px mb-rem16px break-words \" data-identity=\"headline\">What are the risk factors for pox?<\/h4>\n<p class=\"text-gray-800 my-rem16px text-rem19px leading-rem34px \" data-identity=\"paragraph-element\">Anyone can get mpox. The global outbreak appears to be disproportionately affecting men who have sex with men (MSM). On the other hand, in the Clade I outbreak in the Democratic Republic of Congo, children under 15 years old make up more than half the cases.<\/p>\n<p class=\"text-gray-800 my-rem16px text-rem19px leading-rem34px \" data-identity=\"paragraph-element\">In the U.S., you might be at a higher risk of exposure if:<\/p>\n<ul class=\"my-rem16px mx-0 pl-[1.25rem] list-disc marker:text-brandBlue-500 marker:pl-rem24px \" data-identity=\"unordered-list\">\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Someone you&#8217;ve had sex within the past two weeks has been diagnosed with pox.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">You&#8217;ve had sex at a sex club, bathhouse, or another commercial sex venue in the past six months.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">You&#8217;ve had sex at an event or location where pox was spreading.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">You have a sex partner who&#8217;s been in any of the above situations.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">You&#8217;ve been diagnosed with one or more sexually transmitted infections (STIs) in the past six months. This includes acute <a class=\"text-brandBlue-500 underline underline-offset-[5px] decoration-1 break-words hover:text-blue-800 transition\" href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/4251-hiv-aids\" target=\"_blank\" rel=\"noopener\" data-identity=\"link\">HIV<\/a>,\u00a0<a class=\"text-brandBlue-500 underline underline-offset-[5px] decoration-1 break-words hover:text-blue-800 transition\" href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/4217-gonorrhea\" target=\"_blank\" rel=\"noopener\" data-identity=\"link\">gonorrhea<\/a>, syphilis, chancroid, or\u00a0<a class=\"text-brandBlue-500 underline underline-offset-[5px] decoration-1 break-words hover:text-blue-800 transition\" href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/4023-chlamydia\" target=\"_blank\" rel=\"noopener\" data-identity=\"link\">chlamydia<\/a>.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">You&#8217;ve had sex with more than one person in the past six months.<\/li>\n<\/ul>\n<p class=\"text-gray-800 my-rem16px text-rem19px leading-rem34px \" data-identity=\"paragraph-element\">You might be more likely to get severely ill with pox if you:<\/p>\n<ul class=\"my-rem16px mx-0 pl-[1.25rem] list-disc marker:text-brandBlue-500 marker:pl-rem24px \" data-identity=\"unordered-list\">\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Have a weakened immune system, especially if HIV causes it.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Have a history of\u00a0<a class=\"text-brandBlue-500 underline underline-offset-[5px] decoration-1 break-words hover:text-blue-800 transition\" href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/9998-eczema\" target=\"_blank\" rel=\"noopener\" data-identity=\"link\">eczema<\/a>.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Are pregnant.<\/li>\n<\/ul>\n<p class=\"text-gray-800 my-rem16px text-rem19px leading-rem34px \" data-identity=\"paragraph-element\">Babies younger than 1 year old are also at a higher risk for severe illness.<\/p>\n<h3 class=\"text-gray-900 font-bold leading-rem30px text-rem25px bp600:text-rem32px bp600:leading-rem38px mt-rem32px mb-rem16px break-words \" data-identity=\"headline\">What are the complications of pox?<\/h3>\n<p class=\"text-gray-800 my-rem16px text-rem19px leading-rem34px \" data-identity=\"paragraph-element\">Complications caused by pox can include:<\/p>\n<ul class=\"my-rem16px mx-0 pl-[1.25rem] list-disc marker:text-brandBlue-500 marker:pl-rem24px \" data-identity=\"unordered-list\">\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\"><a class=\"text-brandBlue-500 underline underline-offset-[5px] decoration-1 break-words hover:text-blue-800 transition\" href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/24189-bacterial-infection\" target=\"_blank\" rel=\"noopener\" data-identity=\"link\">Bacterial infections<\/a>\u00a0can lead to <a class=\"text-brandBlue-500 underline underline-offset-[5px] decoration-1 break-words hover:text-blue-800 transition\" href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/12361-sepsis\" target=\"_blank\" rel=\"noopener\" data-identity=\"link\">sepsis<\/a>.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Loss of vision or eye damage from pox ocular infections.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Myopericarditis\u00a0(inflammation around your heart).<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\"><a class=\"text-brandBlue-500 underline underline-offset-[5px] decoration-1 break-words hover:text-blue-800 transition\" href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/6058-encephalitis\" target=\"_blank\" rel=\"noopener\" data-identity=\"link\">Encephalitis<\/a>\u00a0(inflammation in your brain).<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\"><a class=\"text-brandBlue-500 underline underline-offset-[5px] decoration-1 break-words hover:text-blue-800 transition\" href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/4471-pneumonia\" target=\"_blank\" rel=\"noopener\" data-identity=\"link\">Pneumonia<\/a>.<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Respiratory distress (extreme difficulty breathing and getting oxygen to your body).<\/li>\n<li class=\"mb-rem12px pl-rem12px text-gray-800 text-rem19px leading-rem34px\">Severe scarring.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-7675 aligncenter\" src=\"https:\/\/i0.wp.com\/www.diabetesasia.org\/magazine\/wp-content\/uploads\/2022\/07\/mnkpx.jpg?resize=300%2C169&#038;ssl=1\" alt=\"mnkpx\" width=\"300\" height=\"169\" srcset=\"https:\/\/i0.wp.com\/www.diabetesasia.org\/magazine\/wp-content\/uploads\/2022\/07\/mnkpx.jpg?resize=300%2C169&amp;ssl=1 300w, https:\/\/i0.wp.com\/www.diabetesasia.org\/magazine\/wp-content\/uploads\/2022\/07\/mnkpx.jpg?resize=768%2C433&amp;ssl=1 768w, https:\/\/i0.wp.com\/www.diabetesasia.org\/magazine\/wp-content\/uploads\/2022\/07\/mnkpx.jpg?w=830&amp;ssl=1 830w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>The 2022 outbreak has a different spread pattern than prior monkeypox outbreaks outside Africa. <sup id=\"cite_ref-Adalja22_58-0\" class=\"reference\"><\/sup>Genetic evidence suggests the outbreak likely started in Nigeria.<sup id=\"cite_ref-:4_59-0\" class=\"reference\"><\/sup><sup id=\"cite_ref-NPR_8-1\" class=\"reference\"><\/sup> Given the unusually high frequency of human-to-human transmission observed in this event and the probable community transmission without a history of traveling to endemic areas, the spread of the virus through close contact is more likely, with a message during sexual activities being the most common route.<sup id=\"cite_ref-:6_60-0\" class=\"reference\"><\/sup>\u00a0Most cases have been in men.<sup id=\"cite_ref-Dye22_61-0\" class=\"reference\"><\/sup>\u00a0A significant proportion of cases, although not all, are in\u00a0<a title=\"Men who have sex with men\" href=\"https:\/\/en.wikipedia.org\/wiki\/Men_who_have_sex_with_men\">men who have sex with men<\/a>\u00a0(MSM), notably in Canada, Spain, and the UK,<sup id=\"cite_ref-Dye22_61-1\" class=\"reference\"><\/sup>\u00a0with many cases diagnosed in sexual health clinics.<sup id=\"cite_ref-Adalja22_58-1\" class=\"reference\"><\/sup> Cases are primarily in young and middle-aged men.<sup id=\"cite_ref-aidsmapmay22_62-0\" class=\"reference\"><\/sup> This points to transmission due to close contact during sex as one transmission route.<sup id=\"cite_ref-Dye22_61-2\" class=\"reference\"><\/sup>\u00a0The\u00a0European Centre for Disease Prevention and Control (ECDC) considers the monkeypox virus moderately transmissible among humans. According to the center, the most common transmission among MSM who contracted the virus is likely through sexual activity due to intimate contact with infected skin lesions. The ECDC rates the likelihood of information due to close contact, including sexual contact, as &#8220;high,&#8221; but without close contact, the possibility of communication between individuals is considered low. <sup id=\"cite_ref-:6_60-1\" class=\"reference\"><\/sup>In\u00a0<i><a title=\"Nature (journal)\" href=\"https:\/\/en.wikipedia.org\/wiki\/Nature_(journal)\">Nature<\/a>,<\/i>\u00a0<a title=\"Anne Rimoin\" href=\"https:\/\/en.wikipedia.org\/wiki\/Anne_Rimoin\">Anne Rimoin<\/a> and Raina MacIntyre speculate that the higher percentage of MSM affected is a result of a coincidental introduction to the community and then sexual activity constituting &#8220;close contact&#8221; rather than the virus itself becoming sexually transmitted.<sup id=\"cite_ref-:7_63-0\" class=\"reference\"><\/sup>\u00a0Monkeypox is not primarily a\u00a0sexually transmitted disease.<sup id=\"cite_ref-Dye22_61-3\" class=\"reference\"><\/sup><\/p>\n<p>On May 23, <a title=\"David L. Heymann\" href=\"https:\/\/en.wikipedia.org\/wiki\/David_L._Heymann\">David Heymann<\/a>, an advisor for the World Health Organization, said that the plausible theory of how the outbreak started was transmitted during sexual intercourse of <a title=\"Gay men\" href=\"https:\/\/en.wikipedia.org\/wiki\/Gay_men\">gay<\/a>\u00a0and\u00a0<a title=\"Bisexuality\" href=\"https:\/\/en.wikipedia.org\/wiki\/Bisexuality\">bisexual men<\/a>\u00a0at two\u00a0<a title=\"Rave\" href=\"https:\/\/en.wikipedia.org\/wiki\/Rave\">raves<\/a>\u00a0in Belgium and Spain.<sup id=\"cite_ref-64\" class=\"reference\"><\/sup> On May 25,\u00a0<i><a title=\"The Guardian\" href=\"https:\/\/en.wikipedia.org\/wiki\/The_Guardian\">The Guardian<\/a><\/i>\u00a0stated that many scientists suspect the disease was circulating in the UK and Europe before reaching the MSM community, possibly misdiagnosed or detected only in isolated cases; four cases were diagnosed in 2018 and 2019, all in individuals recently arrived from Nigeria.<sup id=\"cite_ref-65\" class=\"reference\"><\/sup><\/p>\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-7676 aligncenter\" src=\"https:\/\/i0.wp.com\/www.diabetesasia.org\/magazine\/wp-content\/uploads\/2022\/07\/124836582_c0438048-monkeypox_maculopapular_rash.jpg.webp?resize=300%2C169&#038;ssl=1\" alt=\"monkeypox spread\" width=\"300\" height=\"169\" srcset=\"https:\/\/i0.wp.com\/www.diabetesasia.org\/magazine\/wp-content\/uploads\/2022\/07\/124836582_c0438048-monkeypox_maculopapular_rash.jpg.webp?resize=300%2C169&amp;ssl=1 300w, https:\/\/i0.wp.com\/www.diabetesasia.org\/magazine\/wp-content\/uploads\/2022\/07\/124836582_c0438048-monkeypox_maculopapular_rash.jpg.webp?w=640&amp;ssl=1 640w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/p>\n<p>The UK Human Animal Infections and Risk Surveillance (HAIRS) group warned that the virus could become endemic in wildlife.<sup id=\"cite_ref-67\" class=\"reference\"><\/sup><sup id=\"cite_ref-68\" class=\"reference\"><\/sup><\/p>\n<p>Smallpox vaccines containing\u00a0<a title=\"Vaccinia\" href=\"https:\/\/en.wikipedia.org\/wiki\/Vaccinia\">vaccinia<\/a>, such as\u00a0<a class=\"mw-redirect\" title=\"Imvanex\" href=\"https:\/\/en.wikipedia.org\/wiki\/Imvanex\">Imvanex<\/a> (Jynneos), can provide around 85% effectiveness against monkeypox. This protection level is calculated from studies using smallpox vaccines tested in late 1980 in Africa. The <a title=\"UK Health Security Agency\" href=\"https:\/\/en.wikipedia.org\/wiki\/UK_Health_Security_Agency\">UKHSA<\/a> has begun using Imvanex as post-exposure prophylaxis for close contact with known cases.<sup id=\"cite_ref-100\" class=\"reference\"><\/sup> According to the CDC, the vaccination with Jynneos\/Imvanex is &#8220;[a]dministered as two subcutaneous injections four weeks apart.&#8221;<sup id=\"cite_ref-101\" class=\"reference\"><\/sup><\/p>\n<p>On May 25, disease experts from the <a title=\"National Institute for Communicable Diseases\" href=\"https:\/\/en.wikipedia.org\/wiki\/National_Institute_for_Communicable_Diseases\">NICD<\/a> in South Africa said they saw no need for mass vaccination because they believe cases will not explode as they did in the COVID-19 pandemic.<sup id=\"cite_ref-102\" class=\"reference\"><\/sup><\/p>\n<p>In reaction to the current outbreak of monkeypox, several countries have stated they are buying vaccines and releasing vaccines from national stockpiles for use in the episode. There is a new concern about a vaccine shortage as the demand exceeds the supply.<sup id=\"cite_ref-103\" class=\"reference\"><\/sup>\u00a0In May 2022, the US,<sup id=\"cite_ref-104\" class=\"reference\"><\/sup><sup id=\"cite_ref-:5_105-0\" class=\"reference\"><\/sup>\u00a0Spain,<sup id=\"cite_ref-106\" class=\"reference\"><\/sup> Germany, and the UK announced smallpox vaccine purchases.<\/p>\n<p>On May 24, Centers for Disease Control (CDC) Deputy Director Jennifer McQuiston confirmed the United States is releasing some of their\u00a0<a title=\"Smallpox vaccine\" href=\"https:\/\/en.wikipedia.org\/wiki\/Smallpox_vaccine#MVA-BN\">Jynneos<\/a> vaccine supply from their Strategic National Stockpile for people who are &#8220;high-risk.&#8221;<sup id=\"cite_ref-109\" class=\"reference\"><\/sup><sup id=\"cite_ref-mmwr_110-0\" class=\"reference\"><\/sup><\/p>\n<p>On June 23, the New York City Department of Health announced a clinic at the Chelsea Sexual Health Clinic to offer the two-dose JYNNEOS vaccine to &#8220;&#8230;all gay, bisexual, and other men who have sex with men (cisgender or transgender) ages 18 and older who have had multiple or anonymous sex partners in the last 14 days.&#8221;<sup id=\"cite_ref-111\" class=\"reference\"><\/sup><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Monkeypox Spread: The 2022 monkeypox outbreak began in May and was a significant global health&#8230;<\/p>\n","protected":false},"author":2,"featured_media":6264,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1739,2129,1],"tags":[3447],"class_list":["post-6263","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-environment","category-general-research-update","category-uncategorized","tag-monkeypox"],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.diabetesasia.org\/magazine\/wp-content\/uploads\/2022\/07\/Monkeypox_By_Country.svg_.png?fit=330%2C168&ssl=1","jetpack_sharing_enabled":true,"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/posts\/6263","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/comments?post=6263"}],"version-history":[{"count":8,"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/posts\/6263\/revisions"}],"predecessor-version":[{"id":7679,"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/posts\/6263\/revisions\/7679"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/media\/6264"}],"wp:attachment":[{"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/media?parent=6263"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/categories?post=6263"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/tags?post=6263"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}