More than 400 bioactive compounds have been identified in ginger, with the therapeutic value primarily dependent on gingerols, shogaols, curcumin, paradols, and terpenoids, and 6-gingerol is the most abundant component [2].<\/p>\n
![\"\"](\"https:\/\/i0.wp.com\/www.diabetesasia.org\/magazine\/wp-content\/uploads\/2025\/05\/IJFS-34-001-g001.jpg?resize=348%2C188&ssl=1\")
<\/p>\n
Bioactive compounds of ginger<\/h2>\n
Ginger terpenes such as \u03b1-zingiberene, camphene, ar-curcumene, \u03b2-phellandrene, \u03b2-bisabolene, and \u03b1-piene<\/strong> have antioxidant, anti-inflammatory, and antidiabetic property. Four phenolic components, gingerols, shogaols, parasols, and zingerone are mostly responsible for its therapeutic properties [4].<\/p>\n Anti-inflammatory <\/em>Effect<\/em><\/strong><\/p>\n Ginger significantly lowers TNF-\u03b1, inflammatory factors, and NO synthase. It also reduces different pro- inflammatory markers and inhibits pro-inflammatory cytokines. The most active anti-inflammatory compounds are 6-shogaol, 6-gingerol, and 6-dehydroshogaol of ginger [5].<\/p>\n Antiobesity<\/em> Effect<\/em><\/strong><\/p>\n Gingerenone-A has a higher inhibitory effect on lipid accumulation and adipogenesis than gingerols and 6-gingerol, which appears to activate fatty acid metabolism [6]. Therefore, ginger and its bioactive components are against obesity by increasing lipolysis and inhibiting adipogenesis [3].<\/p>\n Antioxidant<\/em> Effect<\/em><\/strong><\/p>\n \u00a0<\/em>Ginger has great antioxidant activity, increases antioxidant enzymes, decreases oxidative stress, and eradicates free radicals [7] in cancer patients [8].<\/p>\n Antidiabetic<\/em> Effect<\/em><\/strong><\/p>\n \u00a0<\/em>The administration of 6-gingerol modulates glycogen synthase 1 and glucose transporter type 4 (GLUT-4) to the cell membrane, increasing glucose entry in skeletal muscles [9].<\/p>\n Effect on the Lipid Profile<\/em><\/strong><\/p>\n Ginger decreases TGs and LDL without significantly reducing TC. Daily consumption of less than 2 g of ginger powder is more effective in lowering TGs and cholesterol [9].<\/p>\n Antiplatelet Aggregation effect<\/em><\/strong><\/p>\n Consumption of 10 g powdered ginger after four hours significantly reduced adenosine diphosphate (ADP)- and adrenaline-induced platelet aggregation in humans<\/p>\n Effect on the Blood Pressure<\/em><\/strong><\/p>\n \u00a0<\/em>Ginger’s effects on blood pressure can also vary based on dosage, ginger form, duration, experimental model, population, variety of ginger, environmental conditions, and harvest time. 6-Shogaol and 9- gingerol in ginger are responsible for antihypertensive effects [10].<\/p>\n Therefore, clinical trials suggest that, due to the biological functions and cardioprotective properties of ginger and its constituents, it may serve as a new therapeutic agent for various CVDs.<\/p>\n <\/p>\n References <\/strong><\/p>\n The natural components of ginger effectively inhibit inflammation, oxidative stress, and insulin resistance; may reduce…<\/p>\n","protected":false},"author":659,"featured_media":9197,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[25,2215,27],"tags":[],"class_list":["post-9195","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-diabetes-research-update","category-health-update","category-nutrioin-in-disease"],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.diabetesasia.org\/magazine\/wp-content\/uploads\/2025\/05\/garnier_article-header_ginger.webp?fit=890%2C496&ssl=1","jetpack_sharing_enabled":true,"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/posts\/9195","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/users\/659"}],"replies":[{"embeddable":true,"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/comments?post=9195"}],"version-history":[{"count":6,"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/posts\/9195\/revisions"}],"predecessor-version":[{"id":9203,"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/posts\/9195\/revisions\/9203"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/media\/9197"}],"wp:attachment":[{"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/media?parent=9195"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/categories?post=9195"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.diabetesasia.org\/magazine\/wp-json\/wp\/v2\/tags?post=9195"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Ginger Effects<\/h2>\n
\n
<\/h1>\n","protected":false},"excerpt":{"rendered":"